As a society, we are living in ways that don’t always support our optimum health, and this is particularly true when it comes to how we are digesting (or not digesting, as the case may be) our food.
There are a number of root causes of digestive issues that we can relate to our Western lifestyle, and, if these are left unchecked, can result in physical illness and discomfort. Because of our current medical model – which treats symptoms rather than addresses underlying issues – many of the people I see in my clinic with gut and digestive issues have been suffering for a very long time.
The good news is that the Functional Medicine approach has much to offer – in terms of both hope and interventions – for anyone looking to restore and support digestive health.
Many of us can relate to the idea of eating on the go, or reaching for high carb/high sugar snacks in the petrol station as we head off for another busy day. Eating at our desk while we pile through emails and return calls is not alien to us.
And, even if we do eat at home, the foods we are preparing often have an element of convenience – whether they are microwave meals, frozen produce, or take outs.
Our fast-paced lives simply don’t afford the same time to shop for, prepare and enjoy our meals. All of which aid good digestion. I have written more extensively about this topic in a recent blog post titled ‘Why digestion starts with the senses’. You can click here to read the article in full.
In short, however, it’s fair to say that there are a multitude of physiological processes that need to work in harmony in order to aid good digestion.
Many people who have digestive disorders do not always experience obvious symptoms and, in some case, will experience no symptoms whatsoever.
Having said that, health issues associated with digestion and the gut can present in a number of ways, and here I have provided more information about the different issues together with associated symptoms.
Irritable Bowel Syndrome (IBS)
IBS is one of the more common digestive issues, however, it is more complicated than constipation or diarrhoea. IBS affects all members of the population but is more commonly found in women, with an average age of onset between 20 and 40 years old. Up to 1 in 8 people experience symptoms at any particular given time.
There are several subtypes of IBS, based on the predominant symptoms:
Although the exact cause of IBS is currently unknown, Functional GI Disorders describe a group of conditions for which no structural cause has been identified. They occur as a result of disorder of gut-brain communications, and IBS is thought to be a multifaceted disorder involving changes in gastrointestinal motility (the movement of food through the GI tract), heightened pain sensations within the internal organs (hypersensitivity of gastrointestinal nerves), carbohydrate or bile acid malabsorption, emotional stress, gut bacteria imbalance that in turn affects the enteric nervous system, immune system, mucosal barrier and function, the balance of neurotransmitters, the balance of hormones and emotional wellbeing.
IBS and the multifaceted approach. Figure 1 on this link which explains the core and wider-ranging effects.
IBS is characterized by abdominal pain or discomfort that may be associated with an alteration in bowel habits or defecation. Changes in bowel habits can include:
Diarrhoea is defined as loose or watery stools for more than 25% of the time, for a minimum of 3 months. This rapid transit is indicated on The Bristol Stool Chart as types 6/7. This is a common problem, and it is estimated that up to 70% of IBS sufferers experience chronic diarrhea, with half of them experiencing diarrhea most of the time. The other half is said to alternate between diarrhea and constipation. Diarrhoea can have a huge impact on quality of life and can be extremely stressful. What’s more, stress and anxiety can decrease transit time through the gut, therefore resulting in diarrhea, due to the influence on your digestive system by your nervous system. This can lead to a vicious circle of symptoms: diarrhea, resulting in stress, that can cause diarrhea.
Constipation is extremely common, and yet one of the issues we face is in actually defining what constipation is. One of the most common explanations amongst medical professionals is actually constipation is less than Three bowel movements per week. However, most individuals have a differing opinion and as this is such an individual symptom, asking 100 people may produce 100 different answers. When surveyed, 98% reported that they experience between three bowel movements per day and three bowel movements per week. Ideally, we should be emptying our bowels on a daily basis.
On the Bristol Stool Chart below:
Types 1 and 2 (hard lumpy stools) are regarded as a sign of constipation and are usually accompanied by straining, difficulty and discomfort.
Normal transit time varies between 30 – 40 hours. Transit time in IBS can vary between 7 hours (diarrhea) and 96 hours (constipation).
If your transit time is slow (as in constipation), the stool can remain in your colon and become drier as you reabsorb the water it contains – hence the compact shape.
Types 3 and 4 on the chart are the ideal stools, which should be soft and easy to pass.
Bloating occurs when your abdomen feels swollen, distended, windy, full, tight or hard.
Bloating and distension can be caused by different mechanisms. Distension can result from fermentation of fibres by the bacteria in your gut, which can increase gas and therefore swelling. If you are more sensitive and/or feel bloated after eating, this may be the result of the normal pressure of food on the gut wall, which you feel more intensively with IBS. Clinical features of abdominal bloating and distension in IBS are listed in the table below:
Abdominal Pain is a classic feature of IBS and can occur daily, but commonly is present for approximately 3 days per week. IBS-related pain has certain features including:
IBS sufferers tend to be more sensitive in the gut, so may experience pain and discomfort from the normal passage of food or gas. This can result in persistent chronic pain with systemic effects.
Pain signals are communicated through sensory nerve cells in the gut, via the spinal cord, to the brain. If this continually occurs, pain signaling can actually alter your response to how you process pain and the influences of pain perception (throughout the body) which can result in chronic hypersensitivity, meaning that things that should not be painful, actually result in pain (like the passage of food in your gut).Other IBS symptoms include: early satiety, incomplete evacuation of bowels, nausea, indigestion (dyspepsia), swallowing difficulties (dysphagia) and reflux.
IBS is also associated with symptoms beyond the gut. These include
IBS symptoms can happily overlap with other conditions, potentially revealing that differing disease symptoms may be the result of the same underlying causes. There are also diseases/condition that are more common in those with IBS. These include:
Underlying causes of IBS
Functional Disturbances in the following area’s may all feed into Irritable Bowel Syndrome:
Underlying causes Figure 1
Some of the most common reasons I see in my clinic include:
Visceral Hypersensitivity. Heightened gut sensitivity. This may be due to inflammation caused by infection, stress or diet but can remain even if these triggers are removed;
Dysbiosis. Bacterial imbalance in the gut. This can also lead to abnormal levels of serotonin in the gut;
Inflammation. Low grade inflammation is believed to be crucially implicated in the development of IBS, leading to alterations in gut permeability (leaky gut), hypersensitivity of gastrointestinal nerves and alterations in the processing of serotonin.
Intestinal Permeability. For more information about this, you can click here.
Stress. Anxiety and stress frequently present in clients with IBS and can actually arise from gastrointestinal upset. You can read more about stress in my blog post here;
Celiac Disease. Please click here for more information;
Poor Diet. Deficiencies in essential vitamins, minerals and fats and ingestion of certain foods, including gluten, lactose and a predominantly western diet that is high in sugars and carbohydrates may all contribute as dietary triggers to the development of IBS;
Small Intestine Bacterial Overgrowth. Parasitic Infection, dysbiosis (imbalance in your gut bacteria), inflammation, yeast overgrowth and the efficiency of digestion and absorption and gut immune function can all be assessed via functional testing.
The functional approach to IBS involves identifying the underlying causes of the condition and addressing imbalances in digestive function and the lifestyle influences that may be triggering or contributing to the condition. The following video from leading functional medicine doctor Dr Mark Hyman discusses the root causes and solutions to IBS:
IBD – 2
These include Inflammatory Bowel Disease, and other auto immune-diseases that manifest in the gut:
For further information about autoimmune disease, please visit this link.
If you think you are suffering from IBS or any of the IDB disorders and are looking for information on how to overcome it, please get in touch to find out more.
Small Intestine Bacterial Overgrowth (SIBO)
SIBO is characterised by the presence of an abnormally high number and/or type of bacteria present in the small intestine. The small bowel is approximately 20 feet long and normally houses a small number of differing bacteria in comparison to the large bowel.
The small bowel is where we absorb nutrients, where certain bacteria produce nutrients including short chain fatty acids and vitamins including B Vitamins and vitamin K. The small bowel/intestine also houses a crucial proportion of the immune system that provides protection against invading microbes and it also helps neutralize pathogenic (bad) bacteria.
SIBO can affect the digestion and absorption of nutrients potentially resulting in nutritional deficiencies and increased risk of intestinal permeability (or leaky gut) which can ultimately result in increased immune reactions leading to food sensitivities, allergies, inflammation and autoimmune diseases.
There are various reasons why you may have SIBO, however it is mostly found after surgery when we see an overgrowth of bacteria.
SIBO is less likely a result of lifestyle factors.
These additional bacteria found in SIBO typically ferment carbohydrates from the diet and are involved in the development of symptoms which include:
Underlying causes of SIBO
SIBO is due to a failure of 1 or more of the body’s protective mechanisms that prevent bacterial accumulation in the Small Intestine.
Primary Underlying causes:
Small Intestine Motility Deficiency
Chronic conditions of the organs of the digestive system – liver, pancreatitis, kidneys.
SIBO can also be the result of food poisoning. This is an auto-immune condition known as Post-Infectious IBS (PI-IBS), which is thought to account for 2/3 of IBS cases.
However, not all SIBO is PI-IBS and not all SIBO is triggered by food poisoning.
Clinical manifestations of SIBO
SIBO breathe tests can determine the subtype of the condition and the type severity of gas or gases involved. SIBO can be addressed by a combination of diet & lifestyle alterations, herbal antibiotics and in severe cases may require antibiotics from your GP.
SIBO can be a stubborn condition to rebalance, especially as we are all individual and SIBO can vary from person to person. However dietary interventions can be very successful at improving symptoms whilst the underlying causes are investigated.
Functional Medicine Doctor Dr Maxine Barish discusses SIBO in the following short video:
If you think you are suffering from SIBO and are looking for information on how to overcome it, please get in touch to find out more.
References for IBS
Agrawal, A. Whorwell, P. (2007). Review Article: Abdominal Bloating and Distension in Functional Gastrointestinal Disorders – epidemiology and exploration of possible mechanisms, Aliment Pharmacol Ther,27 (1), 2-10.
Bouin, M. Plourde, V. Boivin, B. (2002). Rectal distension testing in patients with irritable bowel syndrome: Sensitivity, specificity, and predictive values of pain sensory thresholds, Gastroenterology, 122 (7): 1771-1777.
Brown, B. (2019). Does Irritable Bowel Syndrome Exist? Identifiable and Treatable causes of associated Symptoms Suggest it May Not, Gastrointest Disord; 1(3):314-340.
Creed, F. Lea, R. Whorwell, P. (2007). Is Visceral Hyposensitivity Associated with Abdominal Distension in Irritable Bowel Syndrome, Gut, 56 (Suppl.2): A62.
Drossman, D. (2016). Functional Gastrointestinal Disorders: History, Pathophysiology, Clinical Features, and Rome IV, Gastroenterology, 150 (6):1262-1279.e2.
Lacy, B. Mearin, F. Chang, L. (2016). Bowel Disorders, Gastroenterology, 150:1393-1407.
Lacy, B. Patel, N. (2017). Rome Criteria and a Diagnostic Approach to Irritable Bowel Syndrome, Journal of Clinical Medicine, Nov, 6 (11): 99.
Leung, R. Riutta, T. Kotecha, J. (2011). Chronic Constipation: An Evidence Based Review, J Am Board Fam Med, Jul-Aug;24 (4): 436-451.
Nicholl, B. Halder, S. Macfarlane, G. (2008). Psychosocial risk markers for new onset irritable bowel syndrome – results of a large prospective population-based study, Pain, Jun 30; 137 (1): 147-155.
Spiller, R. Aziz, Q. Creed, F. (2007). Clinical Services Committee of The British Society of Gastroenterology. Guidelines on the Irritable Bowel Syndrome: mechanisms and practical management. Gut, Dec;56 (12):1770-1798.
Staud, R. Rodriguez, M. (2006). Mechanisms of Disease: Pain in Fibromyalgia Syndrome. Nat Clin Pract Rheumatol, Feb;2 (2): 90-98.
Whorwell, P. McCallum, M. Creed, F. (1986). Non-Colonic Features of Irritable Bowel Syndrome, Gut, Jan;27 (1): 37-40.
Dukowicz, A. Lacy, B. Levine, G. (2007). Small Intestinal Bacterial Overgrowth: A Comprehensive Review, Gastroenterology & Hepatology; 3 (2): 112-122.
Fassano, A. (2012). Leaky Gut and Autoimmune Diseases, Clin Rev Allergy Immunol; 42 (1):71-78.
Morowitz, M. Carlisle, E. Alverdy, J. (2011). Contributions of Intestinal Bacteria to Nutrition and Metabolism in the Critically Ill, Surg Clin North Am, 31 (4): 771-785.
Santaolalla, R. Abrue, M. (2013). Innate Immunity in the Small Intestine, Curr Opin Gastroenterol; 28(2):124-129.
Shah, E. Riddle, M. Chang, C. (2012). Estimating the Contribution of Acute Gastroenteritis to the Overall Prevalence of Irritable Bowel Syndrome, JNM, 18 (2):200-204.
Agrawal, A. Whorwell, P. (2008). Review Artlice: Abdominal Bloating and Distension in Functional Gastrointestinal Disorders – Epidemiology and Exploration of Possible Mechanisms, Aliment Pharmacol Ther; 27, pp.2-10.