What is cholesterol?
Cholesterol is a major sterol in animal tissue, made principally by the liver and is a structural component of every cell membrane in the body and is the precursor to hormones that include estrogens, progesterone, testosterone and cortisol in addition to vitamin D.
It is transported around the body by various (lipo) proteins including LDL, HDL and VLDL – what we have commonly termed good and bad cholesterol – although these terms refer to the carrier, not the actual cholesterol inside the molecule.
LDL – Low density lipoprotein is termed ‘bad’ cholesterol is made by the liver and sent out to body tissues.
HDL – High density lipoprotein is termed ‘good’ cholesterol as it carries cholesterol back from your cells to the liver, to be broken down and eliminated from the body.
High levels of LDL increase the risk of oxidised LDL formation which can fuel atherosclerosis and affect the layer of cells that line the arteries (the endothelium). The build up of LDL in the arteries is often cited as the cause of heart disease but extensive research has failed to show evidence to support a role of dietary cholesterol in the development of cardiovascular disease.
Research has shown that the ratio of LDL to HDL is far more important than each individual level in order to maintain the appropriate balance of lipoproteins.
So what causes high cholesterol?
High cholesterol is influenced by many factors and can result from other imbalances in the body, including high insulin, insulin resistance, excess calories and high triglycerides – which result from eating too many carbohydrates (sugar), high hydrogenated fat intake, stress, lack of physical activity and hypothyrodism.
Diagnosis of Diabetes type II increases your risk of CVD by approx 300%-500%, and is influenced by many factors including:
Hypertension which is associated with insulin resistance in up to 50% of cases, obesity, dyslipidaemia: lipid (fat) abnormalities are associated with insulin resistance and are correlated with cardiovascular risk , exercise, smoking, insulin resistance, inflammation, homocysteine & vitamin status, genetics and epigenetics.
Can we influence cholesterol levels with diet & lifestyle?
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